Numerous new challenges have arisen in the location of oncology clinical trials. New cancer therapies are usually based on cytostatic or targeted agents, which pose new challenges in the design and analysis of all phases of trials. The literature on adaptive trial designs and early stopping has been exploding. Inclusion of high-dimensional data and imaging tactics have turn into widespread practice, and statistical strategies on how to analyse such information have been refined in this area. A compilation of statistica
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