Therapeutic Kinase Inhibitors (Current Topics in Microbiology and Immunology)

Cancer drug development is at present undergoing a profound shift. Drugs targeting basic cellular processes such DNA-replication and microtubule function, frequently referred to as “chemotherapy” and still the backbone of most cancer remedy regimens, are increasingly being complemented by or replaced with kinase inhibitors. This new class of drugs targets enzymes which give growth and survival signals to cancer cells by transferring phosphate groups from Adenosine-5′-triphosphate (ATP)

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